New study: Using AnnoTree to Get More Assignments, Faster, in DIAMOND+MEGAN Microbiome Analysis

Dear MEGAN Community,

I wanted to highlight a new study from our group, where we propose the use of the AnnoTree protein database, rather than NCBI-nr for the DIAMOND+MEGAN pipeline to determine the prokaryotic content metagenomic samples.

For further reading use the link below:

We demonstrated using AnnoTree, there was a 2-fold speedup, increased assignment rates, in particular assigning twice as many reads to KEGG, against the prokaryotic part of NCBI-nr.

Database FastA file and mapping database both can be downloaded from link below: